:root{color:#0f172a;font-synthesis:none;--blue:#0b73d9;--green:#1f9d55;--border:#dde5ee;--muted:#64748b;background:#f6f8fb;font-family:Arial,Helvetica,sans-serif;font-size:16px}*{box-sizing:border-box}body{margin:0}button,input,select,textarea{font:inherit}button{cursor:pointer;color:#334155;background:#fff;border:1px solid #c9d5e3;border-radius:10px;min-height:42px;padding:10px 14px;font-size:.875rem;font-weight:600}button:hover{background:#eaf4ff}button:disabled{opacity:.45;cursor:not-allowed}button:focus-visible,input:focus-visible,select:focus-visible,textarea:focus-visible,summary:focus-visible,a:focus-visible{outline-offset:3px;outline:3px solid #0b73d9}button.primary{color:#fff;background:#0b73d9;border-color:#0b73d9;box-shadow:0 4px 10px #0b73d91a}button.primary:hover{background:#075cad}button.small{min-height:36px;padding:7px 10px;font-size:.8125rem}h1,h2,h3,p{margin:0}h2{font-size:1.125rem;line-height:1.4}h3{margin-bottom:8px;font-size:.9375rem;line-height:1.45}p{line-height:1.55}a{color:#075cad}details summary{cursor:pointer;min-height:28px;font-size:.875rem;font-weight:600;line-height:1.5}details[open]>summary{margin-bottom:14px}.app-shell{max-width:1600px;margin:0 auto;padding:24px 32px 32px}.app-header{justify-content:space-between;align-items:center;gap:20px;min-height:105px;margin-bottom:20px;display:flex}.app-header>img{mix-blend-mode:multiply;width:365px;max-width:65%;height:auto}.header-actions{align-items:center;gap:26px;display:flex}.main-layout{grid-template-columns:minmax(0,1.75fr) minmax(320px,1fr);align-items:start;gap:20px;display:grid}.antibiotic-side,.preparation-side,.drug-column{flex-direction:column;gap:16px;min-width:0;display:flex}.top-fields{grid-template-columns:1.6fr 1fr;gap:16px;display:grid}.top-fields .card{padding:12px}.card{border:1px solid var(--border);background:#fff;border-radius:18px;min-width:0;padding:18px;box-shadow:0 4px 18px #20304a05}.card.compact{padding:16px 18px}.card-heading{justify-content:space-between;align-items:center;gap:10px;margin-bottom:16px;display:flex}.card-heading h2{align-items:center;gap:9px;display:flex}.icon-heading{vertical-align:middle;align-items:center;gap:8px;display:inline-flex}.heading-icon{color:#0b73d9;background:#eaf4ff;border-radius:8px;flex-shrink:0;justify-content:center;align-items:center;width:24px;height:24px;display:inline-flex}.heading-icon svg{width:16px;height:16px}.heading-icon-section{border-radius:10px;width:32px;height:32px}.heading-icon-section svg{width:20px;height:20px}.heading-icon-green{color:#15803d;background:#eaf8ef}.heading-icon-plain{color:currentColor;background:0 0}.heading-icon-plain svg{width:22px;height:22px}.field-grid{grid-template-columns:1fr 1fr;gap:12px;display:grid}.field{border:1px solid var(--border);background:#fff;border-radius:12px;min-width:0;margin:0 0 10px;padding:10px 12px 6px;display:block}.field>span{margin-bottom:4px;font-size:.8125rem;font-weight:600;line-height:1.4;display:block}.field input,.field select,.field>select{color:#0f172a;background:0 0;border:0;width:100%;min-height:29px;padding:3px 0 4px;display:block}.field input::placeholder{color:#94a3b8;font-size:.875rem}.field>div{display:flex}.field small{color:var(--muted)}.field select{font-size:.9375rem}.field:focus-within{border-color:var(--blue)}.field.invalid{border-color:#b91c1c}.field:has(.preset-fill-sweep){position:relative;overflow:hidden}.choices button:has(.preset-fill-sweep){position:relative;overflow:hidden}.field>.preset-fill-sweep,.choices button>.preset-fill-sweep{pointer-events:none;border-radius:inherit;background:linear-gradient(90deg,#0000,#fbbf2447,#fb923c37,#0000);margin:0;animation:1.32s cubic-bezier(.16,1,.3,1) both preset-fill-sweep;position:absolute;inset:0}@keyframes preset-fill-sweep{0%{opacity:0;transform:translate(-100%)}15%{opacity:1}75%{opacity:1}to{opacity:0;transform:translate(100%)}}@media (prefers-reduced-motion:reduce){.field>.preset-fill-sweep,.choices button>.preset-fill-sweep{background:#fbbf2422;animation:none}}.field.missing-field,.choices.missing-field>div>button{background-color:#fff4ed;border-color:#d98565}.choices.missing-field>legend{color:#a33920}[data-validation-pulse=odd] .field.missing-field,[data-validation-pulse=odd] .choices.missing-field>div>button{animation:1.4s ease-in-out missing-field-pulse-odd}[data-validation-pulse=even] .field.missing-field,[data-validation-pulse=even] .choices.missing-field>div>button{animation:1.4s ease-in-out missing-field-pulse-even}@keyframes missing-field-pulse-odd{0%,to{background-color:#fff4ed}40%{background-color:#ffdccb}}@keyframes missing-field-pulse-even{0%,to{background-color:#fff4ed}40%{background-color:#ffdccb}}@media (prefers-reduced-motion:reduce){[data-validation-pulse] .field.missing-field,[data-validation-pulse] .choices.missing-field>div>button{animation:none}}.field-grid .field{margin-bottom:0}.field-grid+.field{margin-top:12px}.exchange-section h2{align-items:center;gap:8px;margin-bottom:16px;display:flex}.muted,.helper{color:var(--muted);font-size:.875rem}.helper{color:#1769aa;white-space:pre-line;margin-top:8px;display:none}.show-helpers .helper{display:block}.helper:empty{display:none}.choices .choice-description{margin:0 0 12px}.prep-introduction{margin-top:0}.prep-workflow-group+.prep-workflow-group{border-top:1px solid var(--border);margin-top:20px;padding-top:16px}.prep-workflow-group+.prep-workflow-group .choices{margin-top:0}.prep-selection-help summary{font-size:.8125rem;font-weight:400}.preline{white-space:pre-line}.prep-summary{color:var(--muted);font-size:.8125rem}.prep-controls{display:none}.prep-controls.expanded{display:block}.choices{border:0;min-width:0;margin:20px 0 0;padding:0}.choices legend{margin-bottom:9px;font-size:.875rem;font-weight:600}.choices>div{flex-wrap:wrap;gap:5px;display:flex}.choices button{flex:1;padding:10px 8px;font-size:.8125rem;font-weight:500}.choices .selected,.output-switch [aria-pressed=true]{color:#075cad;background:#eaf4ff;border-color:#0b73d9}.check{align-items:flex-start;gap:8px;margin:9px 0;font-size:.875rem;line-height:1.5;display:flex}.check input{accent-color:#0b73d9;flex-shrink:0;width:17px;height:17px;margin:3px 0 0}.syringes{border:0;flex-wrap:wrap;gap:4px 15px;margin:18px 0;padding:0;display:flex}.syringes legend{margin-bottom:6px;font-size:.875rem;font-weight:600}.reference-card,.coverage-card{background:#eaf4ff;border:1px solid #d4e5f6;border-radius:14px;padding:16px;font-size:.875rem}.coverage-card{background:#f8fbff}.reference-card p,.coverage-card p{margin:5px 0}.reference-card strong{font-size:1rem}.warning,.caution{color:#9a3412;background:#fff7ed;border-radius:8px;margin-top:10px;padding:10px 12px;font-size:.875rem}.red{color:#b91c1c}.green{color:#15803d}.orange{color:#9a3412}.advisories{border:1px solid var(--border);background:#fff;border-radius:12px;padding:14px;font-size:.875rem}.advisories p+p{margin-top:8px}.advisories>section+section{margin-top:12px}.drug-columns{grid-template-columns:1fr 1fr;gap:16px;display:grid}.dual.main-layout{grid-template-columns:minmax(0,2.4fr) minmax(320px,1fr)}.drug-columns .field-grid{grid-template-columns:1fr}.notes-section{gap:14px;display:grid}.notes-label{font-size:.875rem;font-weight:600;display:block}.notes-label textarea{border:1px solid var(--border);resize:vertical;border-radius:10px;width:100%;margin:10px 0;padding:10px;display:block}.detail-content>*+*{margin-top:12px}.detail-content dl{margin:0}.detail-content dt{margin-top:12px;font-size:.875rem;font-weight:600}.detail-content dd{margin:4px 0 14px;font-size:.875rem;line-height:1.55}.detail-content small{color:var(--muted);font-size:.8125rem}.duration-reference>summary{justify-content:space-between;align-items:center;gap:16px;font-style:italic;list-style:none;display:flex}.duration-reference>summary::-webkit-details-marker{display:none}.duration-reference>summary:after{content:"";border-right:2px solid var(--muted);border-bottom:2px solid var(--muted);flex-shrink:0;width:8px;height:8px;margin-right:4px;transform:rotate(45deg)}.duration-reference[open]>summary:after{transform:rotate(225deg)}.duration-reference-content{padding-top:8px}.duration-reference-table{table-layout:fixed;color:#475569;font-size:.875rem;line-height:1.4}.duration-reference-table th,.duration-reference-table td{border:0;border-bottom:1px solid var(--border);vertical-align:top;overflow-wrap:anywhere;padding:6px 8px}.duration-reference-table th:first-child{width:22%}.duration-reference-table thead{color:#0f172a;background:#f6f8fb}.duration-reference-table tbody th{font-weight:400}.duration-reference-note{border-top:1px solid var(--border);margin-top:16px;padding-top:12px}.duration-reference-note h3{margin-bottom:4px}.duration-reference-note p{color:#475569;font-size:.875rem}.custom-fields{margin-top:10px}.custom-fields .field-grid{margin-top:12px}.action-bar{border:1px solid var(--border);background:#fff;border-radius:16px;grid-template-columns:minmax(240px,1fr) minmax(0,1.4fr) minmax(0,1.4fr);align-items:end;gap:20px;margin:24px 0;padding:16px;display:grid}.eyebrow{letter-spacing:.13em;text-transform:uppercase;color:var(--muted);margin-bottom:8px;font-size:.6875rem;font-weight:700;display:block}.output-switch,.document-actions>div{gap:5px;display:flex}.output-switch button{padding:10px;font-size:.8125rem}@media screen and (width>=900px){.action-bar>:first-child{border-right:1px solid var(--border);padding-right:16px}.action-bar .document-actions{border-left:1px solid var(--border);padding-left:16px}.action-bar .output-switch button,.action-bar .document-actions button{flex:1;min-width:0;min-height:48px}.action-bar .document-actions>div{gap:12px}}.calculate{text-transform:uppercase;letter-spacing:.04em;min-height:48px}.results{outline:none;scroll-margin-top:24px}.dashboard{border:1px solid var(--border);background:linear-gradient(120deg,#f3f8ff,#f3fcf7);border-radius:18px;padding:20px}.results-refreshed .lines strong,.results-refreshed>strong{border-radius:4px;animation:1.4s ease-out both result-amount-refresh}@keyframes result-amount-refresh{0%,20%{background-color:#bfdbfe}to{background-color:#0000}}@media (prefers-reduced-motion:reduce){.results-refreshed .lines strong,.results-refreshed>strong{background-color:#dbeafe;animation:none}}.dashboard>header{justify-content:space-between;align-items:flex-start;gap:12px;margin-bottom:16px;display:flex}.dashboard>header h2{font-size:1.375rem}.dashboard>header .muted{margin-top:5px}.status{color:#15803d;white-space:nowrap;background:#eaf8ef;border-radius:20px;padding:7px 10px;font-size:.75rem}.metric-grid{grid-template-columns:minmax(0,1fr) minmax(0,1fr);gap:14px;display:grid}.metric{border:1px solid var(--border);background:#fbfcfe;border-radius:14px;padding:16px}.metric h3{color:#174b7e}.lines{margin:8px 0 0;padding-left:19px;font-size:.9375rem;line-height:1.6}.lines li+li{margin-top:6px}.result-columns{grid-template-columns:1fr 1fr;gap:20px;display:grid}@media screen and (width>=900px) and (width<=1199px){.result-columns{grid-template-columns:minmax(0,1fr)}}.bag-plan{background:linear-gradient(120deg,#eff6ff,#f0fdf4);margin-bottom:20px}.bag-plan>strong{width:fit-content;margin-top:12px;display:block}.bag-plan>p{margin-top:6px}.results>details{margin-top:18px}.results>details h2{margin:20px 0 12px}.results>details h3{margin-top:16px}.instruction-steps{margin:10px 0 22px;padding-left:25px}.instruction-steps li{margin-bottom:12px;padding-left:4px;line-height:1.6}.notice{background:#eaf4ff;border:1px solid #c9deef;border-radius:10px;justify-content:space-between;align-items:center;margin-bottom:16px;padding:12px 16px;font-size:.875rem;display:flex}.notice button{background:0 0;border:0;min-height:30px;padding:0 10px}.error-panel{z-index:50;color:#991b1b;background:#fff5f5;border:1px solid #fca5a5;border-radius:14px;max-width:min(480px,100vw - 32px);max-height:80vh;padding:20px;position:fixed;top:24px;right:24px;overflow:auto;box-shadow:0 12px 40px #0002}.error-panel button{margin-top:12px}footer{text-align:center;color:var(--muted);margin:25px 0 0;font-size:.8125rem}footer summary{margin-top:12px}.footer-disclaimer{max-width:100ch;margin:8px auto 0;font-size:.875rem}footer ol{text-align:left;line-height:1.6}footer li{overflow-wrap:anywhere;margin-bottom:10px}.help-dialog{border:1px solid var(--border);color:#0f172a;border-radius:18px;width:min(680px,100vw - 30px);max-height:88vh;padding:24px;overflow:auto}.help-dialog::backdrop{background:#0f172a66}.help-dialog header{justify-content:space-between;align-items:center;margin-bottom:20px;display:flex}.help-dialog details{border-top:1px solid var(--border);padding:16px 0}.help-dialog p{margin:10px 0;font-size:.9375rem}.table-scroll{margin:16px 0;overflow-x:auto}table{border-collapse:collapse;width:100%;font-size:.8125rem}th,td{border:1px solid var(--border);text-align:left;padding:8px}.skip-link{position:absolute;top:-100px}.skip-link:focus{z-index:100;background:#fff;padding:10px;top:10px}.mobile-only,.mobile-stepper,.mobile-notice,.mobile-action-bar,.print-document{display:none}@media (width>=900px) and (width<=1150px){.app-shell{padding:20px}.main-layout,.dual.main-layout{grid-template-columns:minmax(0,1.4fr) minmax(300px,1fr)}.drug-columns{grid-template-columns:1fr}.action-bar{gap:12px}}@media (width<=899px){.duration-reference-table th:first-child{width:34%}.desktop-only{display:none!important}.mobile-only{display:block}.app-shell{padding:14px 14px 92px}.app-header{gap:12px;min-height:60px;margin-bottom:15px}.app-header>img{width:245px;max-width:80%}.header-actions{gap:0}.header-actions button{padding:8px 12px}.main-layout,.dual.main-layout{display:block}.antibiotic-side,.preparation-side,.drug-column{gap:14px}.drug-columns{display:block}.drug-columns>.drug-column+.drug-column{margin-top:16px}.card{border-radius:15px;padding:16px}.field-grid{grid-template-columns:1fr}.field{margin-bottom:10px}.field-grid .field{margin-bottom:0}.field-grid{gap:10px}.mobile-stepper{border:1px solid var(--border);background:#fff;border-radius:14px;margin-bottom:14px;padding:14px;display:block}.mobile-step-label{align-items:center;gap:10px;margin-bottom:10px;display:flex}.mobile-step-label .eyebrow{margin:0}.mobile-step-label small{color:var(--muted);margin-left:auto}.mobile-stepper .step-buttons{gap:4px;display:flex}.mobile-stepper button{background:#f1f5f9;border:0;flex:1;min-height:40px;padding:8px 3px;font-size:.75rem}.mobile-stepper button[aria-current=step]{color:#fff;background:#0b73d9}.mobile-notice{color:var(--muted);background:#eef3f8;border-radius:12px;align-items:flex-start;gap:8px;margin-bottom:14px;padding:12px;font-size:.8125rem;display:flex}.mobile-notice button{background:0 0;border:0;min-height:30px;padding:0 8px}.mobile-weight{margin-top:16px}.app-shell .drug-column,.app-shell .notes-section,.app-shell .exchange-section,.app-shell .prep-section,.app-shell .advanced-section,.app-shell .output-section,.app-shell .advisories{display:none}.step-0 .drug-column{display:flex}.step-0 .drug-column>details{display:none}.step-1 .exchange-section{display:block}.step-2 .prep-section,.step-2 .advanced-section{margin-bottom:14px;display:block}.step-2 .prep-controls{display:block}.step-2 .prep-summary{display:none}.step-3 .notes-section{display:grid}.step-3 .drug-column{display:contents}.step-3 .drug-column>*{display:none}.step-3 .drug-column>details{margin-bottom:14px;display:block}.step-4 .output-section,.step-4 .results .advisories{display:block}.action-bar{margin-top:0;padding:14px;display:block}.output-switch{margin-bottom:12px}.output-switch button{flex:1;padding:9px 5px}.action-bar .calculate{display:none}.document-actions>div button{flex:1}.document-actions .eyebrow{margin-top:14px}.result-columns,.metric-grid{grid-template-columns:1fr}.result-columns{gap:16px}.dashboard{border-radius:15px;padding:14px}.status{font-size:.6875rem}.mobile-action-bar{border-top:1px solid var(--border);padding:12px 16px max(12px, env(safe-area-inset-bottom));z-index:20;background:#ffffffed;gap:12px;display:flex;position:fixed;bottom:0;left:0;right:0}.mobile-action-bar button:first-child{flex:1}.mobile-action-bar button:last-child{flex:2}footer{margin-top:24px;font-size:.75rem}.choices>div{flex-direction:column}.choices button{min-height:44px}.help-dialog{padding:18px}.error-panel{top:16px;right:16px}}@media (prefers-reduced-motion:reduce){*{scroll-behavior:auto!important;transition:none!important;animation:none!important}}@media print{@page{size:letter;margin:14mm}@page workflow-summary{size:letter landscape;margin:.38in}@page preparation-instructions{size:letter;margin:9mm 14mm 14mm}.app-shell,.help-dialog{display:none!important}.print-document{color:#000;font-family:Arial,Helvetica,sans-serif;font-size:10pt;line-height:1.4;display:block!important}.print-logo{width:155px;height:auto;margin-bottom:12px}.print-drug{break-before:page}.print-drug:first-child{break-before:auto}.print-document h1{break-after:avoid;margin:0 0 12px;font-size:16pt}.print-document h2{break-after:avoid;margin:14px 0 6px;font-size:12pt}.print-document h3{break-after:avoid;margin:12px 0 6px;font-size:10pt}.print-document p{margin:4px 0;font-size:10pt;line-height:1.4}.print-document li{break-inside:avoid;margin-bottom:7px;font-size:10pt;line-height:1.45}.print-document .lines{margin-bottom:8px;font-size:10pt}.print-document .body_bold{font-weight:700}.print-document .print-notes{white-space:pre-wrap;margin:12px 0}.print-document.print-summary{page:workflow-summary;grid-template-columns:repeat(2,minmax(0,1fr));align-items:stretch;gap:.25in;display:grid!important}.print-summary .print-drug{break-before:auto;overflow-wrap:anywhere;-webkit-box-decoration-break:clone;box-decoration-break:clone;border:.8pt solid #d1dbea;border-radius:8pt;min-width:0;min-height:7.7in;padding:12pt 14pt}.print-summary .print-logo{display:none}.print-summary h1{margin:0;font-size:15pt;line-height:19pt}.print-summary h2{text-underline-offset:2pt;margin:7pt 0 0;font-size:10.5pt;line-height:15pt;-webkit-text-decoration:underline #bcc8d8;text-decoration:underline #bcc8d8}.print-summary p{orphans:2;widows:2;margin:2pt 0 0;font-size:8.8pt;line-height:11pt}.print-summary .product{color:#4f5969;margin:0;font-size:8.7pt}.print-summary .bullet{text-indent:-7pt;padding-left:10pt;font-size:8.6pt;line-height:10.5pt}.print-summary-section{break-inside:avoid}.print-document ol{margin:8px 0 12px;padding-left:22px}.print-instructions{page:preparation-instructions}.print-instruction-heading{break-inside:avoid;break-after:avoid;margin-bottom:6pt}.print-letterhead{margin-bottom:6pt}.print-letterhead .print-logo{width:100pt;margin:0;display:block}.print-instructions h1{margin:0 0 2pt;font-size:20pt;line-height:24pt}.print-instructions p,.print-instructions li{font-size:11pt;line-height:1.3}.print-instructions .print-product{color:#475569;margin:0;font-size:9.5pt}.print-instructions .print-introduction{margin:0 0 7pt;font-size:10pt}.print-instructions h2{margin:9pt 0 4pt}.print-instructions h3{margin:7pt 0 3pt;font-size:11pt}.print-note-block{border-left:2pt solid #94a3b8;margin:7pt 0;padding-left:7pt}.print-note-block h2{margin:0 0 2pt;font-size:10pt}.print-note-block .print-notes{overflow-wrap:anywhere;margin:0}.print-dose-block{break-inside:avoid;border:.8pt solid #64748b;border-radius:4pt;margin:8pt 0;padding:5pt 8pt}.print-dose-block h2{margin:0 0 3pt}.print-dose-block p{margin:2pt 0}.print-bag-details{flex-wrap:wrap;justify-content:space-between;column-gap:18pt;display:flex}.print-bag-details p{overflow-wrap:anywhere;min-width:0}.print-instructions .lines{margin:4pt 0 7pt;padding-left:16pt}.print-instructions .lines li{margin-bottom:0;line-height:1.2}.print-instructions ol{margin:4pt 0 7pt}.print-instructions .instruction-steps li{margin-bottom:4pt}:root,body{background:#fff}}.blue{color:#2563eb}@media (width>=900px) and (width<=1080px){.main-layout,.dual.main-layout{grid-template-columns:minmax(0,1fr)}.drug-columns{grid-template-columns:minmax(0,1fr) minmax(0,1fr)}}@media screen and (width>=1151px),screen and (width>=900px) and (width<=1080px){.drug-columns>.drug-column{grid-row:span 3;grid-template-rows:subgrid;display:grid}.drug-columns>.drug-column>.card:first-child{grid-row:1}.drug-columns>.drug-column>.reference-card{grid-row:2}.drug-columns>.drug-column>details{grid-row:3}.drug-columns .card-heading{min-height:36px}}
